Experience with a new commercial skin testing kit to identify IgE-mediated penicillin allergy.
نویسندگان
چکیده
Many patients who describe a history of allergy to penicillin do not prove to be allergic and can be treated safely with penicillin. After a period of 2 years where testing of penicillin allergy was not possible, a new commercial kit has recently become available. We report our initial experience with use of the kit with 29 patients and discuss one patient who experienced anaphylaxis during i.d. testing.
منابع مشابه
Use of commercial anti-penicillin IgE fluorometric enzyme immunoassays to diagnose penicillin allergy.
BACKGROUND The intermittent unavailability of penicilloyl-polylysine since September 2000 has focused interest on commercial anti-penicillin IgE fluorometric enzyme immunoassay (FEIA) tests to evaluate penicillin allergy. There has been no published comparison of commercial anti-penicillin IgE FEIAs and penicillin skin testing performed in the United States. OBJECTIVE To determine whether the...
متن کاملUtility of minor determinants in penicillin allergy skin testing
Background Penicillin allergy is a major concern among patients and physicians. There’s an estimated 5-10% self reported history of penicillin allergy by patients, but vast majority are not true hypersensitivities. Complete penicillin skin test with both major, minor determinants and amoxicillin is the test of choice for diagnosing IgE-mediated penicillin allergy. While Penicilloyl polylysine (...
متن کاملPenicillin allergies: referral and management practices of anesthesiologists
Rationale Penicillin and other beta-lactams are the most commonly used antibiotics due to their narrow spectrum of activity, low cost and safety profile. However, an “allergy” to Penicillin is also the most commonly reported allergy. Approximately, 5-10% of all patients self-report an allergy to Penicillin and of these <10% are found to have true IgE mediated allergy on skin testing. Numerous s...
متن کاملApproach to Penicillin Allergy – A Survey
Individual approaches to the diagnosis and management of penicillin allergy are practiced by clinicians. This cross-sectional survey of physicians was aimed at exploring their ways of dealing with diagnosis and management of penicillin G allergy. Of the 235 respondents, 63% believed patients’ self-reported history of penicillin allergy and avoided using penic...
متن کاملIntradermal penicillin skin test is more likely to be positive compared to prick skin test in patients with a history of penicillin allergy
Background Penicillin skin testing (PST) with the major determinant (benzyl-penicilloyl) and minor determinant mix (penicillin G, benzyl-penicilloate, and benzyl-penilloate) is one of the major diagnostic tools in the evaluation of a penicillin allergy mediated by IgE. The PST begins with a skin prick test (SP) with the above components and, if negative, then proceeds to an intradermal testing ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Internal medicine journal
دوره 38 5 شماره
صفحات -
تاریخ انتشار 2008